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Effects of Folic Acid and Combinations of Folic Acid and Vitamin B-12 on Plasma Homocysteine Concentrations in Healthy, Young Women

Elevated plasma homocysteine concentrations are considered to be a risk factor for vascular disease and fetal malformations such as neural tube defects. Recent studies have shown that plasma homocysteine can be lowered by folic acid in amounts corresponding to 1-2 times the recommended dietary allowance. Preliminary evidence indicates that vitamin B-12 may be beneficial when included in supplements or in a food-fortification regimen together with folic acid. Read More.

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