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Effect of Mangostin, a Xanthone from Garcinia Mangostana Linn. in Immunopathological and Inflammatory Reactions

Mangostin from the rinds of the fruits of G. mangostana inhibited systemic anaphylaxis, Schultz-Dale's reaction and immunocytoadherence in guinea pigs and rats. It also significantly inhibited the primary and secondary responses of adjuvant-induced arthritis in rats. The results have been correlated with previous findings on the pharmacological effects of mangostin and the probable mode of action is discussed. Read More.

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